Identification of potent P2Y-purinoceptor agonists that are derivatives of adenosine 5′-monophosphate
نویسندگان
چکیده
منابع مشابه
Renal Effects of Adenosine 3 ' , 5 ' - Cyclic Monophosphate and Dibutyryl Adenosine 3 , 5 ' - Cyclic Monophosphate
An abstract of this work appeared in 1970 Abstracts, The American Society of Nephrology. Received for publication 27 October 1970 and in revised form 28 January 1971. similar to the effect of renal arterial infusion of isoproterenol. The results suggest that synthesis of cyclic AMP in proximal renal tubule cells in response to stimulation of beta adrenergic or other receptors can mediate a decr...
متن کاملEffects of adenosine 5'-monophosphate and adenosine 3',5'-cyclic monophosphate on l cells.
The adenine nucleotides, 5'-AMP and 3',5'-cyclic AMP block L cells in the S-phase of the cell cycle. The intracellular level of cyclic AMP is reduced after incubation of cells with 5'-AMP, and rates of uridine transport are increased after incubation with either 5'-AMP or cyclic AMP. On the contrary, cyclic AMP levels are increased and uridine transport decreased in cells treated with an inhibi...
متن کاملIn vivo inhibition of tumor growth by cyclic adenosine 3',5'-monophosphate derivatives.
Asterisks preceding the title refer to studies in humans. 3159 Autobiographical Essay. Alexander Haddow. 3165 Half-life of N-Acetylneuraminic Acid in Plasma Membranes of Rat Liver and Morris Hepatoma 7777. Erik Harms and Werner Reutter. 3173 @ Differential Effects of Rifampicin on Cultured Human Tumor Cells. Wendell D. Winters, Ada L. Tuan, and Donald L. Morton. 3180 The Binding of Vinbiastine ...
متن کاملCyclic adenosine 5'-monophosphate in Escherichia coli.
INTRODUCTION ................ ROLE OF CYCLIC AMP IN REGULATION OF GENE EXPRESSION .......... A Positive Element in Gene Expression ...................................... CRP .......................... :........................................... Direct stimulation of gene expression ...................................... Possible Role As a Negative Element .........................................
متن کاملAn Adenosine 3 ’ , 5 ’ - Monophosphate - de - pendent
In order to provide further information regarding one of the NHzOH-sensitive bonds, the appropriate peptides were subjected to Edman degradation (16) and the phenylthiohydantoin amino acids identified by thin layer chromatography on sheets of silica gel containing a fluorescent indicator (Eastman). Chromatograms were developed with Solvents D and E of Edman and Sjijquist (17). The results of am...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1996
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1996.tb15630.x